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PLA-PEG-PLA三嵌段共聚物的降解性能
发布时间:2025-07-23     作者:zyl   分享到:
医学文献:聚乳酸-聚乙二醇-聚乳酸三嵌段共聚物的化学降解功能笔者:高建文,廖凯荣,全大萍,卢泽俭文章友链:内容提要:A series of polylactic acid (PLA) - polyethylene glycol (PEG) - polylactic acid (PLA) triblock copolymers were prepared by ring opening polymerization of lactide using stannous octoate as initiator and polyethylene glycol as co initiator The influence of PEG molecular weight and propylene ester/PEG molar ratio on the hydrolysis behavior of copolymers was investigated by examining the changes in intrinsic viscosity [η], mass, and thermal behavior of copolymers during hydrolysis in physiological saline The results indicate that PEG blocks have a significant impact on the hydrolysis rate of copolymers When the molar ratio of propylene glycol/PEG is constant, the larger the molecular weight of PEG, the easier it is for the copolymer to hydrolyze; When the PEG block length is constant, the higher the molar ratio of propylene ester/PEG, the slower the hydrolysis rate of the copolymer

PLA-PEG-PLA

以苦不堪言亚锡为导致剂,聚乙二醇大原子为共导致剂进行丙交酯开环聚合反应化学合成了系统聚乳酸(PLA)-聚乙二醇(PEG)-聚乳酸(PLA)三嵌段共聚物.从共聚物在生活生理盐水清淀粉水解时基本特性粘度[η],的品质和热情况的改变,考查了含PEG原子量和丙交酯/PEG摩尔喂料核对共聚物淀粉水解情况的印象.结杲发现,PEG嵌段对共聚物的溶解速率有更重要反应.丙交酯/PEG摩尔进料比一些 时,PEG团伙量越大,共聚物更轻松溶解;PEG嵌段时长一些 时,丙交酯/PEG摩尔进料比越大,共聚物溶解速率较为放缓.有关系举荐:mPEG-CH3mPEG-tri-Glutamic AcidmPEG-di-Glutamic AcidmPEG-FAmPEG-PEI(25K)mPEG-SBAmPEG-PCL(3K)mPEG-SS-C30mPEG-PCL(10K)mPEG-PCL(12K)mPEG-AlkenemPEG-DFmPEG-DBCO以内新闻稿件信息内容因素各种类型中文核心期刊或学术论文,烦请侵犯知识产权请取得联系.我误删!