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DSPE-PEG-TPP功能化MoS₂量子点的构建与表征
发布时间:2025-07-23     作者:zyl   分享到:
学术论文:The role of MoS2 QDs coated with DSPE-PEG-TPP in the protection of protein secondary structure of the brain tissues in an Alzheimer's disease model我们:Ohoud Abdulaziz Alamri a b, Safaa Qusti b, Maha Balgoon b, Abeer A. Ageeli c, F.A. Al-Marhaby d, Abeer M. Alosaimi e, Mohammed A. Jowhari f, Abdu Saeed g 专著超链接: 结语:In a recent groundbreaking study [13], a pioneering approach was employed utilizing MoS2 QDs coated with 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(poly-ethyleneglycol)-2000] (DPSE-PEG) linked with (3-carboxypropyl)triphenylphosphonium bromide (TPP). This innovative compound, recognized for its novel mitochondria-targeted properties, represents a potential therapeutic avenue for AD treatment [13]. The strategic DSPE-PEG-TPP coating layer serves as an essential interface, facilitating the attachment of MoS2 QDs to the mitochondria of microglia cells within brain tissues. Our present investigation builds upon this paradigm, delving into the intricate role of MoS2 coated with DSPE-PEG-TPP in safeguarding the protein secondary structure within brain tissues. Moreover, a comprehensive exploration of the impact of DSPE-PEG-TPP-MoS2 QDs treatment on a spectrum of biomarkers has been meticulously undertaken. Further elucidation of the methodology, detailed results, and an in-depth analysis can be found in subsequent sections, offering a comprehensive understanding of our study. This study sheds light on the role of MoS2 QD in the protection of the protein secondary structure of the brain tissues against AD etiology.

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运用好几个种奠定性的策略,运用涂有1,2-二硬脂酰基-sn-甘油-3-磷工业乙醇胺-N-[氨基(聚乙二醇)-2000](DPSE-PEG)的MoS2量子点,与(3-羧丙基)三苯基溴化鏻(TPP)接触。这个创新性有机化合物以自身的有新意的线粒体靶向药物特征而遭受到教育部认证,是指了阿尔茨海默病的潜在性方法条件。战略定位性的DSPE-PEG-TPP表层不是个必要的表面,提高MoS2-QD粘着在脑机构内小胶质上皮细胞的线粒体上。公司现下的探究建造在一种范式的基本条件上,进一步探究了涂有DSPE-PEG-TPP的MoS2在保护好脑组建内核蛋白三级结构特征部分的繁杂效应。显然,对DSPE-PEG-TPP-MoS2量子点医疗对一型号菌物标志牌物的影晌实行了详细的打磨。后面续章回中还可以进这一步具体探讨的方法、祥细结局和深入浅出探讨,所以全面的清楚咱们的探析。本探析证明了MoS2-QD在守护脑构造淀粉酶质二次构造侵扰AD患病原因功用上的功用。涉及推荐英文:mPEG-RGDmPEG-SS-CELmPEG-PLGA(30K)mPEG-PLGA(75:25)(5K)mPEG-DTA (ALC-0159) CAS No.: 1849616-42-7mPEG-DMG CAS No.: 160743-62-4mPEG-NBmPEG-PLA(15K)mPEG-PLGA(1K)mPEG-PLGA(10K)mPEG-PLGA(20K)mPEG-PEI(1K)左右论文项目的来源各种各样中文核心期刊或学术论文,烦请侵犯著作权请沟通让我们清空!