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多肽RGD修饰的海藻酸钠,RGD-Sodium alginate
发布时间:2022-04-11     作者:zyl   分享到:

RGD掩盖的海带酸钠Sodium alginateDSPE-PCB20男女性甜菜碱缩聚物胶束缩聚度/RGD遮盖的绿豆酸钠DSPE-PCB 男女性甜菜碱整合物胶束

食用两性关系甜菜碱汇聚物胶束(DSPE-PCB)来模拟衣壳病毒的表面特征(图1a),并封装模型蛋白。聚羧酸甜莱碱(PCB)通过质子辅助氨基酸转运蛋白1(PAT1)穿透上皮细胞层(图1b)。PAT1可以促进甜菜碱和甜菜碱衍生物渗透到上皮细胞层。

Because of the sharp contrast in polarity between the superhydrophilic tail and the superhydrophobic head of DSPE–PCB 5K, its micelles stabilize docetaxel at extremely dilute conditions, at which conventional micelles dissociate. In vivo, the ultrastability of the formulation enables a larger amount of drug to reach the tumour through the enhanced permeability and retention effect. Chemical structure reproduced from ref. 8, Macmillan Publishers Ltd.

RGD-Sodium alginate

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仅应应应用于应应应用于研发,未能应应应用于机体检验(zyl 2022.04.11)