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小分子交联剂蛋白-蛋白以及蛋白-核酸大分子复合体材料
发布时间：2021-03-25     作者：wyf   分享到：
小分子结构结构热塑剂血清-血清各类血清-核酸分子结构结构pp体材质

现阶段常见的小大分子热塑剂基本与梦想蛋白质Lys有机酸等残基反馈，且不具备时间与空间辩别率。进展小大分子热塑剂并能活性聊天与好几个有机酸等残基做好热塑并具备时间与空间辩别率并能加速血清质双方功用的探究。

带异光保护好的醌甲基化物（QM）小团伙催化化学热塑剂。使用的这样的化学热塑剂，需要根据远紫外线光（365 nm）分析于是特情人的施放滋养的醌甲基化物使用氨基酸质-膳食纤维质并且膳食纤维质-核酸相互之间的热塑。仅能够表明蛋清热塑兑换的时间分辩率，对接的强可溶性的醌甲基化物可与不少附近的亲核性的残基，如 His、Lys、Tyr 等侧链体现而产生了血清交连。从而这个交连剂不只是使实用每个血清的交连，也需要在神经细胞核裂解液和在活体神经细胞核中引发血清-蛋白质时有发生有机化学化学交联。

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提炼那端有带醌甲基化物前体，另那端有带NHS酯基的小氧分子无机化学交连剂（NHQM）。依据对14-3-3 梦想蛋白质UV紫外线光线射并不一定各种加没有加NHQM交连剂治理 ，出现只剩下在添加NHQM交连剂以及分光光度计光环境射下会会诱导性产生了14-3-3二聚体。因此一种二聚体的生成了行更好的顺利通过光控时时的生成了。进一大步表明了NHQM化学交联剂的进来其中一个配用性-不错怏速辩认血清配位聚合情況，还有灵活运用物理交连质在14-3-3球蛋白上与醌甲基化物反应迟钝的亲和性残基。

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又，测量了NHQM在体细胞膜内的热塑情況，表明体细胞膜身体内热塑有效率薄弱，这很有可能与短期间内NHQM穿膜性和析出力差关与，而上升穿膜时间段NHS会便捷蛋白质水解所以使交连没有效果

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杏彩体育平台 供应产品：

新产品大全框：

DHB

2,5-dihydroxybenzoic acid

CAS Number: 490-79-9

CHCA

α-Cyano-4-hydroxycinnamic acid

CAS Number: 28166-41-8

HABA

2-(4'-Hydroxybenzeneazo)benzoic acid

CAS Number: 1634-82-8

Sinapinic Acid  

CAS Number: 530-59-6

THAP

2',4',6'-Trihydroxyacetophenone monohydrate

CAS Number: 480-66-0

DHAP

2',4',-Dihydroxyacetophenone

CAS Number: 89-84-9

MBT

MBT MALDI matrix, 2-Mercaptobenzothiazole

CAS Number: 149-30-4

 

 

色谱有关系化学试剂

新产品所有：

LCMS Grade Solvents：

LCMS Acetonitrile     CAS Number: 75-05-8

LCMS Acetonitrile with 0.1% Acetic Acid

LCMS Acetonitrile with 0.1% Formic Acid

LCMS Acetonitrile with 0.1% TFA

LCMS Acetonitrile with 0.1% Formic Acid and 0.01% TFA

LCMS Water with 0.1% Acetic Acid

LCMS Water with 0.1% Formic Acid

LCMS Methanol       CAS Number: 67-56-1

LCMS Water          CAS Number: 7732-18-5

HPLC Grade Solvents：

HPLC Acetone           CAS Number: 67-64-1

HPLC Acetonitrile        CAS Number: 75-05-8

HPLC Acetonitrile with 0.1% TFA

HPLC Cyclohexane       CAS Number: 110-82-7

HPLC Dimethyl sulfoxide  CAS Number: 67-68-5

HPLC Methanol        ;  CAS Number: 67-56-1

HPLC Water             CAS Number: 7732-18-5

Acetic Acid Ampules (Proteomics Grade)    CAS Number: 64-19-7

Formic Acid Ampules (Proteomics Grade)    CAS Number: 64-18-6

TFA Ampules (Proteomics Grade)          CAS Number: 76-05-1

HFBA Ampules (Proteomics Grade)         CAS Number: 375-22-4

Formic Acid + TFA Ampules (Proteomics Grade)

LCMS Mobile Phases Sampler Pack

Additives & Ion Pairing：

 

Proteochem球蛋清交连采血管，原装进口球蛋清交连采血管

Protein crosslinkers （蛋白酶热塑相应生化试剂）：

Heterobifunctional Crosslinkers弧型双系统交连剂：

SMCC Crosslinker

Succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate

CAS Number: 64987-85-5

Sulfo-SMCC Crosslinker

Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate

CAS Number: 92921-24-9

Sulfo-SANPAH Crosslinker

N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate

CAS Number: 102568-43-4

SMPH Crosslinker

Succinimidyl-6-[ß-maleimidopropionamido]hexanoate

PDPH Crosslinker

3-[2-Pyridyldithio]propionyl hydrazide) is a cleavable, carbohydrate reactive

MBS Crosslinker

m-Maleimidobenzoyl-N-hydroxysuccinimide ester

CAS Number: 58626-38-3

Sulfo-MBS Crosslinker

m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester

SPDP Crosslinker

N-Succinimidyl 3-[2-pyridyldithio]-propionate

CAS Number: 68181-17-9

LC-SPDP Crosslinker  

Succinimidyl 6-(3-[2-pyridyldithio]-propionamido)hexanoate

Sulfo-LC-SPDP Crosslinker

Sulfosuccinimidyl 6-(3'-[2-pyridyldithio]-propionamido)hexanoate

SIA Crosslinker

N-Succinimidyl iodoacetate

CAS Number: 39028-27-8

SBA Crosslinker

N-Succinimidyl bromoacetate; SIB crosslinker

CAS Number: 42014-51-7

SMPB Crosslinker

N-Succinimidyl 4-[4-maleimidophenyl]butyrate

CAS Number: 79886-55-8

BMPS Crosslinker

N-(ß-Maleimidopropyloxy)succinimide ester

CAS Number: 55750-62-4

EMCS Crosslinker

N-[e-Maleimidocaproyloxy]succinimide ester

CAS Number: 55750-63-5

GMBS Crosslinker

N-[Gamma-Maleimidobutyryloxy] Succinimide

CAS Number: 80307-12-6

ANB-NOS Crosslinker

N-5-Azido-2-nitrobenzoyloxysuccinimide

CAS Number: 60117-35-3

Homobifunctional Crosslinkers同型双能力化学交联剂：

BS3 Crosslinker

Bis[sulfosuccinimidyl] suberate

CAS Number: 82436-77-9

DSS Crosslinker

Disuccinimidyl suberate   N-hydroxysuccinimide ester

CAS Number: 68528-80-3

BS2G Crosslinker

BS2G; Bis[Sulfosuccinimidyl] glutarate

DSG Crosslinker

Disuccinimidyl glutarate; Di(N-succinimidyl

CAS Number: 79642-50-5

DSP Crosslinker

3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester)

CAS Number: 57757-57-0

DTSSP Crosslinker

3,3´-Dithiobis[sulfosuccinimidylpropionate

CAS Number: 81069-02-5

Sulfo-EGS Crosslinker

glycolbis(sulfosuccinimidylsuccinate)

CAS Number: 167410-92-6

EGS Crosslinker

Ethylene glycolbis(succinimidylsuccinate)

CAS Number: 70539-42-3

DST Crosslinker  

CAS Number: 62069-75-4

Zero-Length Crosslinkers - EDC-HCl, Sulfo-NHS & NHS：

EDC-HCl

1- Ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride

CAS Number: 25952-53-8

Sulfo-NHS

N-hydroxysulfosuccinimide  Hydroxy-2,5-dioxopyrrolidine-3-sulfonicacid

CAS Number: 106627-54-7

 

进口报关蛋清质化学交联化学试剂列表页，Sulfo-LC-SPDP

Protein crosslinkers （淀粉酶化学交联一些化学制剂）：

Heterobifunctional Crosslinkers异形双功能表化学交联剂：

SMCC Crosslinker           CAS Number: 64987-85-5

Sulfo-SMCC Crosslinker      CAS Number: 92921-24-9

Sulfo-SANPAH Crosslinker    CAS Number: 102568-43-4

SMPH Crosslinker

PDPH Crosslinker

MBS Crosslinker             CAS Number: 58626-38-3

Sulfo-MBS Crosslinker

SPDP Crosslinker            CAS Number: 68181-17-9

LC-SPDP Crosslinker  

Sulfo-LC-SPDP Crosslinker

SIA Crosslinker              CAS Number: 39028-27-8

SBA Crosslinker             CAS Number: 42014-51-7

SMPB Crosslinker           CAS Number: 79886-55-8

BMPS Crosslinker           CAS Number: 55750-62-4

EMCS Crosslinker           CAS Number: 55750-63-5

GMBS Crosslinker          CAS Number: 80307-12-6

ANB-NOS Crosslinker        CAS Number: 60117-35-3

Homobifunctional Crosslinkers同型双功用热塑剂：

BS3 Crosslinker           CAS Number: 82436-77-9

DSS Crosslinker           CAS Number: 68528-80-3

BS2G Crosslinker

DSG Crosslinker          CAS Number: 79642-50-5

DSP Crosslinker           CAS Number: 57757-57-0

DTSSP Crosslinker       ; CAS Number: 81069-02-5

Sulfo-EGS Crosslinker     CAS Number: 167410-92-6

EGS Crosslinker          CAS Number: 70539-42-3

DST Crosslinker          CAS Number: 62069-75-4

Zero-Length Crosslinkers - EDC-HCl, Sulfo-NHS & NHS：

EDC-HCl               CAS Number: 25952-53-8

Sulfo-NHS              CAS Number: 106627-54-7

Deuterated Crosslinker BS3-d4

Deuterated Crosslinker BS2G-d4

Deuterated Crosslinker DSS-d4

上面的品牌杏彩体育平台 微生物均可产生，仅使用于科研项目！wyf 03.25